PHYTOCHEMICAL ANALYSIS AND THE ANTI-INFLAMMATORY ACTIVITIES OF METHANOL EXTRACT OF CRATEVA ADANSONII

CHAPTER ONE

1.0 INTRODUCTION

Anti inflammatory refers to the property of a substance or treatment that reduces inflammation. Anti –inflammatory drugs make up about half of analgesics, reducing pain by inhibiting inflammation as opposed to opioids, which affect the central nervous system published by Artemis Morris, molly Rossiter.

Inflammation (Latin, inflammo, “ the complex biological response of vascular tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. The classical signs of inflammation are pain, heat, redness, swelling and loss of function by Dr Weil. Inflammation is a protective attempt by the organism to remove the injurious stimuli and initiate the healing process.

Inflammation is not a synonym for infection, even in cases where inflammation is caused by infection. Although infection is caused by a microorganism, and organism pathogen. Inflammation is a setereotyped response and is considered as a mechanism of innate immunity by Dr. Weil.

TYPES OF INFLAMMATION

Inflammation can be classified as either acute or chronic. Acute inflammation, is the initial response of the body to harmful stimuli and is achieved by the increased movement of plasma and leukocytes (especially granulocytes) from the blood into the injured tissues.

  Prolonged inflammation, known as chronic inflammation, leads to a progressive shift in the type of cells present at the site of inflammation and is characterized by simultaneous destruction and healing of the tissues from the inflammatory process from Wikipedia, the free encyclopedia. 

AIMS AND OBJECTIVES.

Evaluation of the anti –inflammatory activity of crateva adansonii (plant). The purpose of this study was to evaluate and compare the anti-inflammatory activity of the aqueous sten bark extract of crateva adansonii in experimental acute and chronic inflammatory animal models. And to evaluate the phytochemical constituents and pharmacological evaluation of the effect of crateva adansonii on albino rats.

 

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